"ДНК-паспорт моей собаки" - программа Genoscoper Laboratorie

[Bergerbs]

В конце августа, когда мы посетили ЕвроДогШоу 2013г в Швейцарии, на стенде института генетических исследований собак Genoscoper Laboratories я сдала на анализ букальный эпителий своих собак: Атаки и Армады прямо на стенде этого института. Через три недели мне пришло письмо, из которого я узнала, что Армада имеет индекс генетического здоровья, равный 96 баллам (при среднем по нашей породе 100 баллов), и что букальный эпителий Атаки был взят недостаточно корректно, поэтому результат получить не удалось, и что нужно будет этот тест пересдать.
Я лечу в Хельсинки 13 декабря - специально, чтобы самой поговорить со специалистами института, чтобы отвезти туда образцы букального эпителия других собак - моих собственных и собак моих друзей.
Если кому-то необходимо, я могу захватить с собой образцы - и передать их представителям Genoscoper Laboratories.
http://us6.campaign-archive1.com/?u=522 ... 5739a73885
Это ссылка на руссифицированный фрагмент сайта института.

[Bergerbs]

Вот какое письмо я получила от Genoscoper Laboratories:


...Индекс Генетического Здоровья - показатель динамический и меняется в
зависимости от количества и результатов протестированных собак в базе
MyDogDNA.
На все протестированные нами заболевания ваши собаки чисты.

Главное, на что нужно обратить внимание, это на уровень гетерозиготности
собак:
- Атака - 27.2%
- Армада - 26,5%
Оба результата - замечательны!
Средний/нормальный уровень гетерозиготности современных собак - 30%. Чем
этот процент выше - тем лучше. Если уровень инбридинга начинает расти, то
процент гетерозиготности патает.

[Bergerbs]

А вот - кому интересно - как выглядит генетический паспорт Армады ИЗББ
https://www.mydogdna.com/crm/animal/en/ ... /disorders
Генетический паспорт Атаки ИЗББ выглядит так:
https://www.mydogdna.com/crm/animal/en/ ... /disorders

[МишЛен]

Мария, ссылки, которые даны в вашем последнем сообщении, не открываются. А хотелось бы посмотреть...

[Bergerbs]

Да, ссылки - не открываются, сама попробовала... Но - не удивительно, это - конфиденциальная для многих информация! Поэтому - прошу простить за нечитабельность - только так получилось скопировать:

MyDogDNA PASS – 8700 2321 7749 059
Nickname: Armada
Breed: White Swiss Shepherd Dog
Registered name: Armada Iz Beloy Brigady
Registration ID: RKF 3232738
Tattoo / Microchip: 643094100144891
Gender: Female
Owner: Maria Gurieva
Country:
DNA profile: ISAG (Official): 870023217749059
Genetic
Health Index

The Genetic Health Index (GHI) provided by the MyDogDNA Pass describes the relative health level of the dog’s genome in relation to the other tested dogs in the MyDogDNA database by combining the measured disease heritage and genetic diversity. Your dog’s GHI is not stable and it is likely to change when the number of tested dogs increases. The average dog has a GHI value of 100 - the healthier the dog, the higher the index. For instance, severe inherited diseases as well as low genetic diversity lower the index. The GHI value becomes breed-specific only after a sufficient number of dogs have been tested within breed.

Please note that the GHI value should not be used for breeding selections – mating of two dogs with high GHI will not necessarily lead to healthier offspring (they might after all be closely related).

84
1. Genetic Disorders
2. Conformation
3. Genetic Diversity
4. Genetic Relationships
A majority of the genetic disorders reported below follow either a recessive (autosomal or X-linked) or dominant pattern of inheritance. The results are reported as Clear, Carrier or Affected for recessive and Clear or Affected for dominant disorders.

The genotype column reports the actual genotype of your dog at the measured site of the genome. At each site, your dog carries two alleles (genetic variants), separated by a forward slash: one inherited from its dam, and the other from its sire. E.g. for a dominantly inherited disorder, this column reveals whether an affected dog is heterozygous or homozygous for the disease mutation (i.e., carries one or two copies of it). Without examination of the parents’ genomes, it is not possible to tell which one of the alleles is inherited from the dam and which from the sire.

Please read the disease descriptions carefully, should your dog turn out to be a carrier or affected and share this information also with your veterinarian. In particular, note that any condition may exhibit incomplete penetrance on the phenotypic level, and the onset, expression and progressivity of the disease may be influenced by other genetic and environmental factors. For instance, not all dogs with the result “Affected” will necessarily manifest the condition.

Note that the disease severity rating presented here is only suggestive and it should not be used for other purposes. Always consult your veterinarian for the most accurate information on your dog’s health status and available treatment options.

Symbols
See documentation about the prevalence within breed
Carrier
Affected
In Study
No call

Tested Disorders Results Genotype i
Prevalence i
All dogsWithin breed Severity i
Blood disorders

Bleeding disorder due to P2RY12 defect
Clear -/- 0.00%
{data.s*100}%

Canine Cyclic Neutropenia (Gray Collie Syndrome)
Clear -/- 0.00%
{data.s*100}%

Canine Leucocyte Adhesion Deficiency (CLAD), type I
Clear G/G 0.00%
{data.s*100}%

Factor IX Deficiency or Haemophilia B, Gly379Glu mutation
Clear G/G 0.00%
{data.s*100}%

Factor IX Deficiency or Haemophilia B; mutation originally found in Lhasa Apso
Clear G/G 0.00%
{data.s*100}%

Factor VII Deficiency
Clear G/G 0.00%
{data.s*100}%

Factor VIII deficiency or Haemophilia A; mutation originally found in German Shepherd
Clear G/G 0.00%
{data.s*100}%

Glanzmann Thrombasthenia (GT), Type I; mutation originally found in Pyrenean Mountain Dog
Clear C/C 0.00%
{data.s*100}%

Glycogen Storage Disease VII or Hereditary Phosphofructokinase (PFK) Deficiency
Clear G/G 0.00%
{data.s*100}%

May-Hegglin Anomaly (MHA)
Clear G/G 0.00%
{data.s*100}%

Pyruvate Kinase Deficiency of Erythrocyte; mutation originally found in Beagle
Clear G/G 0.00%
{data.s*100}%

Pyruvate Kinase Deficiency of Erythrocyte; mutation originally found in Labrador Retriever
Clear C/C 0.05%
{data.s*100}%

Pyruvate Kinase Deficiency of Erythrocyte; mutation originally found in Pug
Clear T/T 0.00%
{data.s*100}%

Pyruvate Kinase Deficiency of Erythrocyte; mutation originally found in West Highland White Terrier
Clear -/- 0.00%
{data.s*100}%

Trapped Neutrophil Syndrome (TNS)
Clear -/- 0.05%
{data.s*100}%

Von Willebrand's Disease (vWD) Type III; mutation originally found in Kooikerhondje
Clear G/G 0.00%
{data.s*100}%

Von Willebrand's Disease (vWD) Type III; mutation originally found in Shetland Sheepdog
Clear -/- 0.00%
{data.s*100}%
Cardiological disorders

Dilated Cardiomyopathy; mutation originally found in Doberman Pinscher (USA)
No call 0.14%
{data.s*100}%
Endocrine disorders

Hypothyroidism; mutation originally found in Tenterfield Terrier
Clear C/C 0.00%
{data.s*100}%

Hypothyroidism; mutation originally found in Toy Fox- and Rat Terrier
Clear C/C 0.00%
{data.s*100}%
Eye disorders

Achromatopsia or Cone Degeneration (CD); mutation originally found in German Shorthaired Pointer
Clear G/G 0.00%
{data.s*100}%

Autosomal Dominant Progressive Retinal Atrophy (ADPRA)
Clear C/C 0.00%
{data.s*100}%

Canine Multifocal Retinopathy 1 (cmr1), Mastiff-related breeds mutation
Clear C/C 0.14%
{data.s*100}%

Canine Multifocal Retinopathy 2 (cmr2); mutation originally found in Coton de Tulear
Clear G/G 0.05%
{data.s*100}%

Canine Multifocal Retinopathy 3 (cmr3); mutation 1 originally found in Lapponian Herder
Clear -/- 0.05%
{data.s*100}%

Canine Multifocal Retinopathy 3 (cmr3); mutation 2 originally found in Lapponian Herder
Clear G/G 0.05%
{data.s*100}%

Collie Eye Anomaly (CEA)
Clear -/- 0.96%
{data.s*100}%

Cone-rod dystrophy (crd SWD); mutation originally found in Standard Wire-haired Dachshund
Clear -/- 0.00%
{data.s*100}%

Congenital Stationary Night Blindness (CSNB)
Clear A/A 0.00%
{data.s*100}%

Generalized Progressive Retinal Atrophy; mutation originally found in Schapendoes
Clear -/- 0.00%
{data.s*100}%

Golden Retriever Progressive Retinal Atrophy 1 (GR_PRA 1)
Clear -/- 0.92%
{data.s*100}%

Primary Hereditary Cataract (PHC); mutation originally found in Australian Shepherd
Clear -/- 0.32%
{data.s*100}%

Primary Lens Luxation (PLL)
Clear G/G 2.11%
{data.s*100}%

Primary Open Angle Glaucoma; mutation originally found in Beagle
Clear G/G 0.00%
{data.s*100}%

Rod-Cone Dysplasia 1 (rcd1); mutation originally found in Irish Setter
Clear G/G 0.00%
{data.s*100}%

Rod-Cone Dysplasia 1a (rcd1a); mutation originally found in Sloughi
Clear -/- 0.00%
{data.s*100}%

Rod-Cone Dysplasia 3 (rcd3)
Clear -/- 0.00%
{data.s*100}%

X-Linked Progressive Retinal Atrophy 1 (XLPRA1)
Clear -/- 0.00%
{data.s*100}%
Immunological disorders

Autosomal Recessive Severe Combined Immunodeficiency (ARSCID)
Clear A/A 0.00%
{data.s*100}%

C3 deficiency
Clear -/- 0.00%
{data.s*100}%

X-linked Severe Combined Immunodeficiency (XSCID); mutation originally found in Basset Hound
Clear -/- 0.00%
{data.s*100}%

X-linked Severe Combined Immunodeficiency (XSCID); mutation originally found in Cardigan Welsh Corgi
Clear -/- 0.00%
{data.s*100}%
Kidney disorders

Autosomal Recessive Hereditary Nephropathy (ARHN); mutation originally found in English Cocker Spaniel
Clear A/A 0.00%
{data.s*100}%

Autosomal Recessive Hereditary Nephropathy (ARHN); mutation originally found in English Springer Spaniel
Clear C/C 0.00%
{data.s*100}%

Hyperuricosuria and Hyperuricemia (HUU) or Urolithiasis
Clear G/G 1.01%
{data.s*100}%

Polycystic Kidney Disease (PKD)
Clear G/G 0.00%
{data.s*100}%

Primary hyperoxaluria (PH); mutation originally found in Coton de Tulear
Clear G/G 0.05%
{data.s*100}%

X-linked Hereditary Nephropathy (XLHN)
Clear G/G 0.00%
{data.s*100}%
Metabolic disorders

Glycogen Storage Disease, Type Ia (GSDIa)
Clear G/G 0.00%
{data.s*100}%

Glycogen Storage Disease, type II or Pompe's disease
Clear G/G 1.01%
{data.s*100}%

Glycogen Storage Disease, type IIIa (GSDIIIa)
Clear -/- 0.00%
{data.s*100}%

Hypocatalasia or Acatalasemia
Clear G/G 0.00%
{data.s*100}%

Mucopolysaccharidosis Type I (MPSI)
Clear G/G 0.00%
{data.s*100}%

Mucopolysaccharidosis Type IIIA (MPSIIIA); mutation originally found in Dachshund
Clear C/C 0.00%
{data.s*100}%

Mucopolysaccharidosis Type IIIA (MPSIIIA); mutation originally found in New Zealand Huntaway
Clear -/- 0.00%
{data.s*100}%

Mucopolysaccharidosis Type VI (MPSVI); mutation originally found in Poodle
Clear -/- 0.00%
{data.s*100}%

Mucopolysaccharidosis Type VII; mutation originally found in Brazilian Terrier
Clear C/C 0.32%
{data.s*100}%

Pyruvate Dehydrogenase Deficiency
Clear C/C 0.00%
{data.s*100}%
Muscular disorders

Cavalier King Charles Spaniel Muscular Dystrophy (CKCS-MD)
Clear G/G 0.00%
{data.s*100}%

Duchenne-like Muscular Dystrophy, Pembroke Welsh Corgi-type
Clear T/T 0.00%
{data.s*100}%

Muscular Dystrophy, Duchenne type or Golden Retriever Muscular Dystrophy (GRMD)
Clear A/A 0.00%
{data.s*100}%

Myotonia; mutation originally found in Miniature Schnauzer
Clear C/C 0.00%
{data.s*100}%

Myotubular Myopathy 1 or X-linked Myotubular Myopathy
Clear C/C 0.00%
{data.s*100}%
Neurological disorders

Adult-onset Neuronal Ceroid Lipofuscinosis, mutation originally found in Tibetan terrier
Clear -/- 0.09%
{data.s*100}%

Bandera's Neonatal Ataxia (BNAt)
Clear -/- 0.00%
{data.s*100}%

Benign Familial Juvenile Epilepsy or Remitting Focal Epilepsy
Clear A/A 2.62%
{data.s*100}%

Cerebellar abiotrophy or neonatal cerebellar cortical degeneration (NCCD)
Clear -/- 0.09%
{data.s*100}%

Degenerative Myelopathy (DM)
Clear G/G 2.07%
{data.s*100}%

Fetal-onset Neuroaxonal Dystrophy (FNAD)
Clear G/G 0.00%
{data.s*100}%

GM1 Gangliosidosis; mutation originally found in Alaskan Husky
Clear -/- 0.00%
{data.s*100}%

GM1 Gangliosidosis; mutation originally found in Shiba Dog
Clear -/- 0.00%
{data.s*100}%

GM2 Gangliosidosis
Clear -/- 0.00%
{data.s*100}%

L-2-hydroxyglutaric Aciduria (L2HGA), Yorkshire Terrier mutation
Clear A/A 0.00%
{data.s*100}%

L-2-hydroxyglutaric Aciduria (L2HGA); mutation 1 originally found in Staffordshire Bull Terrier
Clear T/T 0.00%
{data.s*100}%

L-2-hydroxyglutaric Aciduria (L2HGA); mutation 2 originally found in Staffordshire Bull Terrier
Clear C/C 0.00%
{data.s*100}%

Neonatal Encephalopathy with Seizures (NEWS)
Clear T/T 0.09%
{data.s*100}%

Neuronal Ceroid Lipofuscinosis 1 (NCL1)
Clear -/- 0.00%
{data.s*100}%

Neuronal Ceroid Lipofuscinosis 10 (NCL10)
Clear G/G 0.00%
{data.s*100}%

Neuronal Ceroid Lipofuscinosis 2 (NCL2)
Clear C/C 0.00%
{data.s*100}%

Neuronal Ceroid Lipofuscinosis 4A (NCL4)
Clear G/G 0.00%
{data.s*100}%

Neuronal Ceroid Lipofuscinosis 5 (CLN5)
Clear C/C 0.00%
{data.s*100}%

Neuronal Ceroid Lipofuscinosis 6 (NCL6)
Clear T/T 0.00%
{data.s*100}%

Polyneuropathy; mutation originally found in Alaskan Malamute
Clear G/G 0.09%
{data.s*100}%

Polyneuropathy; mutation originally found in Greyhound
Clear -/- 0.00%
{data.s*100}%

Progressive early-onset cerebellar ataxia; mutation originally found in Finnish Hound
Clear T/T 1.06%
{data.s*100}%
Neuromuscular disorders

Alpha Fucosidosis
Clear -/- 0.00%
{data.s*100}%

Episodic falling (EF)
Clear -/- 0.05%
{data.s*100}%

Exercise-Induced Collapse (EIC)
Clear G/G 1.33%
{data.s*100}%

GM1 Gangliosidosis; mutation originally found in Portuguese Water Dog
Clear G/G 0.00%
{data.s*100}%

Globoid Cell Leukodystrophy (GLD) or Krabbe's disease, Terrier mutation
Clear A/A 0.00%
{data.s*100}%

Globoid Cell Leukodystrophy (GLD) or Krabbe's disease; mutation originally found in Irish Setter
Clear -/- 0.00%
{data.s*100}%

Hyperekplexia or Startle Disease
Clear G/G 0.00%
{data.s*100}%
Pharmacogenetics

Ivermectin sensitivity
Clear -/- 0.83%
{data.s*100}%

Malignant Hyperthermia (MH)
Clear T/T 0.00%
{data.s*100}%
Skeletal disorders

Chondrodysplasia; mutation originally found in Norwegian Elkhound and Karelian Bear Dog
Clear C/C 1.61%
{data.s*100}%

Craniomandibular Osteopathy (CMO)
Clear C/C 0.00%
{data.s*100}%

Oculo-Skeletal Dysplasia 2 or Dwarfism-Retinal Dysplasia 2
Clear -/- 0.00%
{data.s*100}%

Osteogenesis imperfecta (OI); mutation originally found in Dachshund
Clear T/T 0.00%
{data.s*100}%

Skeletal Dysplasia 2 (SD2)
Clear G/G 0.41%
{data.s*100}%
Skin disorders

Anhidrotic Ectodermal Dysplasia or X-linked Ectodermal Dysplasia (XHED)
Clear G/G 0.00%
{data.s*100}%

Ectodermal dysplasia or Skin Fragility Syndrome (ED-SFS)
Clear G/G 0.00%
{data.s*100}%

Epidermolysis bullosa, dystrophic
Clear G/G 0.05%
{data.s*100}%

Epidermolytic Hyperkeratosis or Ichthyosis in Norfolk Terrier
Clear G/G 0.00%
{data.s*100}%

Golden Retriever Ichtyosis
Clear C/C 2.66%
{data.s*100}%

Lamellar Ichthyosis (LI)
Clear -/- 0.00%
{data.s*100}%

Musladin-Lueke syndrome (MLS)
Clear C/C 0.00%
{data.s*100}%
Other disorders

Congenital Keratoconjuctivitis Sicca and Ichthyosiform Dermatosis (CKCSID) or Dry Eye Curly Coat Syndrome
Clear -/- 0.00%
{data.s*100}%

Gallbladder Mucocele Formation
Clear -/- 0.00%
{data.s*100}%

Narcolepsy; mutation originally found in Dobermann
Clear -/- 0.00%
{data.s*100}%

Persistant Mullerian Duct Syndrome (PMDS), mutation originally found in Miniature Schnauzer
Clear C/C 0.00%
{data.s*100}%

Primary Ciliary Dyskinesia (PCD)
Clear C/C 0.00%
{data.s*100}%
See next: Conformation

[Bergerbs]

А это - Тачкин паспорт

Ataka
MyDogDNA PASS
MyDogDNA Breeder™
MyDogDNA PASS – 8700 2321 7746 659
Nickname: Ataka
Breed: White Swiss Shepherd Dog
Registered name: Ataka Iz Beloy Brigady
Registration ID: RKF 3232734
Tattoo / Microchip: 643094100136568
Gender: Female
Owner: Maria Gurieva
Country:
DNA profile: ISAG (Official): 870023217746659
Genetic
Health Index

The Genetic Health Index (GHI) provided by the MyDogDNA Pass describes the relative health level of the dog’s genome in relation to the other tested dogs in the MyDogDNA database by combining the measured disease heritage and genetic diversity. Your dog’s GHI is not stable and it is likely to change when the number of tested dogs increases. The average dog has a GHI value of 100 - the healthier the dog, the higher the index. For instance, severe inherited diseases as well as low genetic diversity lower the index. The GHI value becomes breed-specific only after a sufficient number of dogs have been tested within breed.

Please note that the GHI value should not be used for breeding selections – mating of two dogs with high GHI will not necessarily lead to healthier offspring (they might after all be closely related).

85
1. Genetic Disorders
2. Conformation
3. Genetic Diversity
4. Genetic Relationships
A majority of the genetic disorders reported below follow either a recessive (autosomal or X-linked) or dominant pattern of inheritance. The results are reported as Clear, Carrier or Affected for recessive and Clear or Affected for dominant disorders.

The genotype column reports the actual genotype of your dog at the measured site of the genome. At each site, your dog carries two alleles (genetic variants), separated by a forward slash: one inherited from its dam, and the other from its sire. E.g. for a dominantly inherited disorder, this column reveals whether an affected dog is heterozygous or homozygous for the disease mutation (i.e., carries one or two copies of it). Without examination of the parents’ genomes, it is not possible to tell which one of the alleles is inherited from the dam and which from the sire.

Please read the disease descriptions carefully, should your dog turn out to be a carrier or affected and share this information also with your veterinarian. In particular, note that any condition may exhibit incomplete penetrance on the phenotypic level, and the onset, expression and progressivity of the disease may be influenced by other genetic and environmental factors. For instance, not all dogs with the result “Affected” will necessarily manifest the condition.

Note that the disease severity rating presented here is only suggestive and it should not be used for other purposes. Always consult your veterinarian for the most accurate information on your dog’s health status and available treatment options.

Symbols
See documentation about the prevalence within breed
Carrier
Affected
In Study
No call

Tested Disorders Results Genotype i
Prevalence i
All dogsWithin breed Severity i
Blood disorders

Bleeding disorder due to P2RY12 defect
Clear -/- 0.00%
{data.s*100}%

Canine Cyclic Neutropenia (Gray Collie Syndrome)
Clear -/- 0.00%
{data.s*100}%

Canine Leucocyte Adhesion Deficiency (CLAD), type I
Clear G/G 0.00%
{data.s*100}%

Factor IX Deficiency or Haemophilia B, Gly379Glu mutation
Clear G/G 0.00%
{data.s*100}%

Factor IX Deficiency or Haemophilia B; mutation originally found in Lhasa Apso
Clear G/G 0.00%
{data.s*100}%

Factor VII Deficiency
Clear G/G 0.00%
{data.s*100}%

Factor VIII deficiency or Haemophilia A; mutation originally found in German Shepherd
Clear G/G 0.00%
{data.s*100}%

Glanzmann Thrombasthenia (GT), Type I; mutation originally found in Pyrenean Mountain Dog
Clear C/C 0.00%
{data.s*100}%

Glycogen Storage Disease VII or Hereditary Phosphofructokinase (PFK) Deficiency
Clear G/G 0.00%
{data.s*100}%

May-Hegglin Anomaly (MHA)
Clear G/G 0.00%
{data.s*100}%

Pyruvate Kinase Deficiency of Erythrocyte; mutation originally found in Beagle
Clear G/G 0.00%
{data.s*100}%

Pyruvate Kinase Deficiency of Erythrocyte; mutation originally found in Labrador Retriever
Clear C/C 0.05%
{data.s*100}%

Pyruvate Kinase Deficiency of Erythrocyte; mutation originally found in Pug
Clear T/T 0.00%
{data.s*100}%

Pyruvate Kinase Deficiency of Erythrocyte; mutation originally found in West Highland White Terrier
Clear -/- 0.00%
{data.s*100}%

Trapped Neutrophil Syndrome (TNS)
Clear -/- 0.05%
{data.s*100}%

Von Willebrand's Disease (vWD) Type III; mutation originally found in Kooikerhondje
Clear G/G 0.00%
{data.s*100}%

Von Willebrand's Disease (vWD) Type III; mutation originally found in Shetland Sheepdog
Clear -/- 0.00%
{data.s*100}%
Cardiological disorders

Dilated Cardiomyopathy; mutation originally found in Doberman Pinscher (USA)
Clear -/- 0.14%
{data.s*100}%
Endocrine disorders

Hypothyroidism; mutation originally found in Tenterfield Terrier
Clear C/C 0.00%
{data.s*100}%

Hypothyroidism; mutation originally found in Toy Fox- and Rat Terrier
Clear C/C 0.00%
{data.s*100}%
Eye disorders

Achromatopsia or Cone Degeneration (CD); mutation originally found in German Shorthaired Pointer
Clear G/G 0.00%
{data.s*100}%

Autosomal Dominant Progressive Retinal Atrophy (ADPRA)
Clear C/C 0.00%
{data.s*100}%

Canine Multifocal Retinopathy 1 (cmr1), Mastiff-related breeds mutation
Clear C/C 0.14%
{data.s*100}%

Canine Multifocal Retinopathy 2 (cmr2); mutation originally found in Coton de Tulear
Clear G/G 0.05%
{data.s*100}%

Canine Multifocal Retinopathy 3 (cmr3); mutation 1 originally found in Lapponian Herder
Clear -/- 0.05%
{data.s*100}%

Canine Multifocal Retinopathy 3 (cmr3); mutation 2 originally found in Lapponian Herder
Clear G/G 0.05%
{data.s*100}%

Collie Eye Anomaly (CEA)
Clear -/- 0.96%
{data.s*100}%

Cone-rod dystrophy (crd SWD); mutation originally found in Standard Wire-haired Dachshund
Clear -/- 0.00%
{data.s*100}%

Congenital Stationary Night Blindness (CSNB)
Clear A/A 0.00%
{data.s*100}%

Generalized Progressive Retinal Atrophy; mutation originally found in Schapendoes
Clear -/- 0.00%
{data.s*100}%

Golden Retriever Progressive Retinal Atrophy 1 (GR_PRA 1)
Clear -/- 0.92%
{data.s*100}%

Primary Hereditary Cataract (PHC); mutation originally found in Australian Shepherd
Clear -/- 0.32%
{data.s*100}%

Primary Lens Luxation (PLL)
Clear G/G 2.11%
{data.s*100}%

Primary Open Angle Glaucoma; mutation originally found in Beagle
Clear G/G 0.00%
{data.s*100}%

Rod-Cone Dysplasia 1 (rcd1); mutation originally found in Irish Setter
Clear G/G 0.00%
{data.s*100}%

Rod-Cone Dysplasia 1a (rcd1a); mutation originally found in Sloughi
Clear -/- 0.00%
{data.s*100}%

Rod-Cone Dysplasia 3 (rcd3)
Clear -/- 0.00%
{data.s*100}%

X-Linked Progressive Retinal Atrophy 1 (XLPRA1)
Clear -/- 0.00%
{data.s*100}%
Immunological disorders

Autosomal Recessive Severe Combined Immunodeficiency (ARSCID)
Clear A/A 0.00%
{data.s*100}%

C3 deficiency
Clear -/- 0.00%
{data.s*100}%

X-linked Severe Combined Immunodeficiency (XSCID); mutation originally found in Basset Hound
Clear -/- 0.00%
{data.s*100}%

X-linked Severe Combined Immunodeficiency (XSCID); mutation originally found in Cardigan Welsh Corgi
Clear -/- 0.00%
{data.s*100}%
Kidney disorders

Autosomal Recessive Hereditary Nephropathy (ARHN); mutation originally found in English Cocker Spaniel
Clear A/A 0.00%
{data.s*100}%

Autosomal Recessive Hereditary Nephropathy (ARHN); mutation originally found in English Springer Spaniel
Clear C/C 0.00%
{data.s*100}%

Hyperuricosuria and Hyperuricemia (HUU) or Urolithiasis
Clear G/G 1.01%
{data.s*100}%

Polycystic Kidney Disease (PKD)
Clear G/G 0.00%
{data.s*100}%

Primary hyperoxaluria (PH); mutation originally found in Coton de Tulear
Clear G/G 0.05%
{data.s*100}%

X-linked Hereditary Nephropathy (XLHN)
Clear G/G 0.00%
{data.s*100}%
Metabolic disorders

Glycogen Storage Disease, Type Ia (GSDIa)
Clear G/G 0.00%
{data.s*100}%

Glycogen Storage Disease, type II or Pompe's disease
Clear G/G 1.01%
{data.s*100}%

Glycogen Storage Disease, type IIIa (GSDIIIa)
Clear -/- 0.00%
{data.s*100}%

Hypocatalasia or Acatalasemia
Clear G/G 0.00%
{data.s*100}%

Mucopolysaccharidosis Type I (MPSI)
Clear G/G 0.00%
{data.s*100}%

Mucopolysaccharidosis Type IIIA (MPSIIIA); mutation originally found in Dachshund
Clear C/C 0.00%
{data.s*100}%

Mucopolysaccharidosis Type IIIA (MPSIIIA); mutation originally found in New Zealand Huntaway
Clear -/- 0.00%
{data.s*100}%

Mucopolysaccharidosis Type VI (MPSVI); mutation originally found in Poodle
Clear -/- 0.00%
{data.s*100}%

Mucopolysaccharidosis Type VII; mutation originally found in Brazilian Terrier
Clear C/C 0.32%
{data.s*100}%

Pyruvate Dehydrogenase Deficiency
Clear C/C 0.00%
{data.s*100}%
Muscular disorders

Cavalier King Charles Spaniel Muscular Dystrophy (CKCS-MD)
Clear G/G 0.00%
{data.s*100}%

Duchenne-like Muscular Dystrophy, Pembroke Welsh Corgi-type
Clear T/T 0.00%
{data.s*100}%

Muscular Dystrophy, Duchenne type or Golden Retriever Muscular Dystrophy (GRMD)
Clear A/A 0.00%
{data.s*100}%

Myotonia; mutation originally found in Miniature Schnauzer
Clear C/C 0.00%
{data.s*100}%

Myotubular Myopathy 1 or X-linked Myotubular Myopathy
Clear C/C 0.00%
{data.s*100}%
Neurological disorders

Adult-onset Neuronal Ceroid Lipofuscinosis, mutation originally found in Tibetan terrier
Clear -/- 0.09%
{data.s*100}%

Bandera's Neonatal Ataxia (BNAt)
Clear -/- 0.00%
{data.s*100}%

Benign Familial Juvenile Epilepsy or Remitting Focal Epilepsy
Clear A/A 2.62%
{data.s*100}%

Cerebellar abiotrophy or neonatal cerebellar cortical degeneration (NCCD)
Clear -/- 0.09%
{data.s*100}%

Degenerative Myelopathy (DM)
Clear G/G 2.07%
{data.s*100}%

Fetal-onset Neuroaxonal Dystrophy (FNAD)
Clear G/G 0.00%
{data.s*100}%

GM1 Gangliosidosis; mutation originally found in Alaskan Husky
Clear -/- 0.00%
{data.s*100}%

GM1 Gangliosidosis; mutation originally found in Shiba Dog
Clear -/- 0.00%
{data.s*100}%

GM2 Gangliosidosis
Clear -/- 0.00%
{data.s*100}%

L-2-hydroxyglutaric Aciduria (L2HGA), Yorkshire Terrier mutation
Clear A/A 0.00%
{data.s*100}%

L-2-hydroxyglutaric Aciduria (L2HGA); mutation 1 originally found in Staffordshire Bull Terrier
Clear T/T 0.00%
{data.s*100}%

L-2-hydroxyglutaric Aciduria (L2HGA); mutation 2 originally found in Staffordshire Bull Terrier
Clear C/C 0.00%
{data.s*100}%

Neonatal Encephalopathy with Seizures (NEWS)
Clear T/T 0.09%
{data.s*100}%

Neuronal Ceroid Lipofuscinosis 1 (NCL1)
Clear -/- 0.00%
{data.s*100}%

Neuronal Ceroid Lipofuscinosis 10 (NCL10)
Clear G/G 0.00%
{data.s*100}%

Neuronal Ceroid Lipofuscinosis 2 (NCL2)
Clear C/C 0.00%
{data.s*100}%

Neuronal Ceroid Lipofuscinosis 4A (NCL4)
Clear G/G 0.00%
{data.s*100}%

Neuronal Ceroid Lipofuscinosis 5 (CLN5)
Clear C/C 0.00%
{data.s*100}%

Neuronal Ceroid Lipofuscinosis 6 (NCL6)
Clear T/T 0.00%
{data.s*100}%

Polyneuropathy; mutation originally found in Alaskan Malamute
Clear G/G 0.09%
{data.s*100}%

Polyneuropathy; mutation originally found in Greyhound
Clear -/- 0.00%
{data.s*100}%

Progressive early-onset cerebellar ataxia; mutation originally found in Finnish Hound
Clear T/T 1.06%
{data.s*100}%
Neuromuscular disorders

Alpha Fucosidosis
Clear -/- 0.00%
{data.s*100}%

Episodic falling (EF)
Clear -/- 0.05%
{data.s*100}%

Exercise-Induced Collapse (EIC)
Clear G/G 1.33%
{data.s*100}%

GM1 Gangliosidosis; mutation originally found in Portuguese Water Dog
Clear G/G 0.00%
{data.s*100}%

Globoid Cell Leukodystrophy (GLD) or Krabbe's disease, Terrier mutation
Clear A/A 0.00%
{data.s*100}%

Globoid Cell Leukodystrophy (GLD) or Krabbe's disease; mutation originally found in Irish Setter
Clear -/- 0.00%
{data.s*100}%

Hyperekplexia or Startle Disease
Clear G/G 0.00%
{data.s*100}%
Pharmacogenetics

Ivermectin sensitivity
Clear -/- 0.83%
{data.s*100}%

Malignant Hyperthermia (MH)
Clear T/T 0.00%
{data.s*100}%
Skeletal disorders

Chondrodysplasia; mutation originally found in Norwegian Elkhound and Karelian Bear Dog
Clear C/C 1.61%
{data.s*100}%

Craniomandibular Osteopathy (CMO)
Clear C/C 0.00%
{data.s*100}%

Oculo-Skeletal Dysplasia 2 or Dwarfism-Retinal Dysplasia 2
Clear -/- 0.00%
{data.s*100}%

Osteogenesis imperfecta (OI); mutation originally found in Dachshund
Clear T/T 0.00%
{data.s*100}%

Skeletal Dysplasia 2 (SD2)
Clear G/G 0.41%
{data.s*100}%
Skin disorders

Anhidrotic Ectodermal Dysplasia or X-linked Ectodermal Dysplasia (XHED)
Clear G/G 0.00%
{data.s*100}%

Ectodermal dysplasia or Skin Fragility Syndrome (ED-SFS)
Clear G/G 0.00%
{data.s*100}%

Epidermolysis bullosa, dystrophic
Clear G/G 0.05%
{data.s*100}%

Epidermolytic Hyperkeratosis or Ichthyosis in Norfolk Terrier
Clear G/G 0.00%
{data.s*100}%

Golden Retriever Ichtyosis
Clear C/C 2.66%
{data.s*100}%

Lamellar Ichthyosis (LI)
Clear -/- 0.00%
{data.s*100}%

Musladin-Lueke syndrome (MLS)
Clear C/C 0.00%
{data.s*100}%
Other disorders

Congenital Keratoconjuctivitis Sicca and Ichthyosiform Dermatosis (CKCSID) or Dry Eye Curly Coat Syndrome
Clear -/- 0.00%
{data.s*100}%

Gallbladder Mucocele Formation
Clear -/- 0.00%
{data.s*100}%

Narcolepsy; mutation originally found in Dobermann
Clear -/- 0.00%
{data.s*100}%

Persistant Mullerian Duct Syndrome (PMDS), mutation originally found in Miniature Schnauzer
Clear C/C 0.00%
{data.s*100}%

Primary Ciliary Dyskinesia (PCD)
Clear C/C 0.00%
{data.s*100}%
See next: Conformation

[Bergerbs]

Тестирование производится более чем по сотне известных генетических болезней - в том числе: DM, порок сердца, болезни глаз, нервной системы, костной системы, имунной, пищеварения, кожных заболеваний...
Цель - создать достаточно широкую базу данных для заводчиков, чтобы те подбирали пару для вязки из генетически здоровых животных.

[Bergerbs]

Cardiological disorders

Dilated Cardiomyopathy; mutation originally found in Doberman Pinscher (USA)
No call 0.14%
{data.s*100}%

А вот за это исследование - я особенно благодарна - недавно познакомилась с Мариной Кургановой - кардиологом из Беланты - она заводчик доберманов, Катя ее собак тоже выставляет - так она мне рассказала - про то, какое это страшное дело - недостаточность сердечного клапана...

[Яна]

Отличная информация. Спасибо!
А нужна ли родословная для проведения теста?

[Bergerbs]

НЕ ОБЯЗАТЕЛЬНО... Но - можно.